Do familial neural tube defects breed true?

NEURAL TUBE DEFECTS IN NEWBORNS IN THE SOUTH-EAST OF THE CASPIAN SEA BORDER (GORGAN, IRAN 1998-2000)

Neural tube defects (NTD) are one of the most important malformations of newborns. The aim of this research is to determine the rates of NTD, anencephaly and spina bifida cystica and the relations of these abnormalities to the factors including sex, race, ethnicity, maternal age and familial marriage in the south-east of the Caspian Sea border. A three-year descriptive-analytic and cross-s...

Is there a familial link between Down's syndrome and neural tube defects? Population and familial survey.

OBJECTIVE To verify whether Down's syndrome and neural tube defects arise more often in the same family than expected by chance. DESIGN Population and familial survey. SETTING Network of maternity hospitals in the Latin American collaborative study of congenital malformations (ECLAMC) in Argentina, Bolivia, Brazil, Chile, Colombia, Ecuador, Paraguay, Peru, Uruguay, and Venezuela between 198...

Effect of arsenic on neural tube in mouse embryo and relation to reduced folate carrier (RFC-1)

Arsenic is an important environmental toxicant which is usually found in drinking water in inorganic form. The hypothesis tested in this investigation is; arsenic exposure causes neural tube defects (NTDs) andthese defects of the central nervous system are more likely related to folate deficiency during fetal life. In this study, sodium arsenate was administered via intraperitoneal route at a r...

The combinations of the sexes of familial cases of neural tube defect.

اثرات تراتوژنیک فنی‌‌توئین برتکوین لوله عصبی و اسکلتی‌جنین‌های موش سوری

Abstract Background: Phenytoin is one of the oldest anti epileptic drugs it may result in fetal abnormalities if taken during pregnancy. This study was designed to determine teratogenic effects of phenytoin on the development of skeleton and neural tube defects in mouse fetuses.. Materials and methods: Forty small experimental pregnant mice (NMRI Type) were divided in to three experimental...